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Job Overview

We are seeking a highly motivated and skilled individual to join our team as a Computational Immunology Scientist.

Key points

  1. AbbVie Immunology is expanding its discovery Systems Immunology team in Cambridge, Massachusetts.

  2. The team is focused on identifying new targets for the treatment of autoimmune and chronic inflammatory diseases through computational analysis of human disease tissue-derived…

  3. The successful candidate will develop and implement computational approaches to understand disease biology and drug responses using high-throughput molecular profiling data.

  4. This role will involve integrating single-cell RNA-seq, scATAC-seq, TCR/BCR repertoire, bulk RNA-seq, and Olink proteomics data to characterize disease-associated cell states…

  5. Hands-on scRNA-seq analysis experience or experience with scATAC-seq or TCR/BCR analysis, with interest in developing expertise across both.

  6. Proficiency in Python and/or R and experience working in Linux-based computing environments.

  7. Experience with commonly used bioinformatics tools and frameworks such as Scanpy, AnnData, Cell Ranger, scvi-tools, DESeq2, GSEA, WGCNA, or related methods.

  8. Working knowledge of statistical analysis, multiple-testing correction, batch effects, and biological replication in high-dimensional datasets.

Skills

PythonAWSLinuxDeep LearningStatisticsCommunication

Experience: Entry-level · 5–7 years · Job type: Full-time